Is Aging a Disease? Epigenetics with David Sinclair & Neil deGrasse Tyson

From StarTalk.

Is aging a disease that can be cured? Neil deGrasse Tyson and cohosts Chuck Nice and Gary O’Reilly discover the field of epigenetics, the Information Theory of Aging, and curing blindness for mice with Professor of Genetics at Harvard Medical School, David Sinclair.

What is epigenetics? Discover the difference between genetics and epigenetics. We discuss whether aging is a disease and if there have been any changes in aging throughout the centuries. David breaks down the information theory of aging and how epigenetic inheritance works. Plus, Chuck tells us about some of the studies he’s reading and how behaviors during your lifetime can be epigenetically passed onto your children.

Could we someday cure death? What does aging look like in the broader animal kingdom? We look at aging from an evolutionary standpoint, restoring vision in blind mice, and what the length of your telomeres tells you. We break down conflicting information regarding diet and how to not just live longer but live younger, longer. What are the genes that control aging?

We break down what anti-aging medicine would look like and whether it would be affordable for everyday people. Learn about the world’s oldest mice with the youngest eyes. We discuss the Yamanaka genes and how they can be utilized to turn back time on a cellular level. Is DNA destiny?

Thanks to our Patrons Jason L, Daniel Holzmann, Anne P Vance, Unknown, Myles G Blanton, Paul A. Straus, and Gregory Dees for supporting us this week.

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Science meets pop culture on StarTalk! Astrophysicist & Hayden Planetarium director Neil deGrasse Tyson, his comic co-hosts, guest celebrities & scientists discuss astronomy, physics, and everything else about life in the universe. Keep Looking Up!

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00:00 – Introduction – David Sinclair
02:28 – What Are Epigenetics?
5:03 – Is Aging A Disease?
7:33 – Information Theory of Aging
9:31 – Epigenetic Inheritance
15:23 – Do Some People Age Differently?
16:56 – Could We Never Die?
21:13 – Is DNA Our Destiny?
22:23 – Aging in the Animal Kingdom
24:30 – Curing Blindness
27:29 – Telomere Length, OSK Therapy, & The Hallmarks of Aging
30:35 – StarTalk Patreon
32:18 – Can You Cure Aging?
34:25 – Neil Wants Immortal Mice
36:58 – Using AI for Gene Therapy
38:17 – NAD & Yamanaka Genes
40:48 – Biological Stress & Lifestyle Effects on Aging
45:23 – Closing Thoughts