From Reactions.
Correction: 1:43 The left side of the graph should be labeled as Celsius, and the right side should be labeled as Fahrenheit.
Ethylene glycol is the most common ingredient in automotive antifreeze. But for years it was used in homicidal poisonings. What made this household chemical so dangerous? And why is it no longer a viable poison?
#chemistry #poison #antifreeze
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Sources:
Intentional Ethylene Glycol Poisoning Increase after Media Coverage of Antifreeze Murders
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117604/
Woman pleads guilty to killing husband with antifreeze
https://www.delawareonline.com/story/news/local/2017/02/06/woman-pleads-guilty-killing-husband-antifreeze/97544316/
Homicidal Ethylene Glycol Intoxication
https://journals.lww.com/amjforensicmedicine/Abstract/2006/06000/Homicidal_Ethylene_Glycol_Intoxication__A_Report.11.aspx
Ethylene glycol poisoning: Quintessential clinical toxicology; analytical conundrum
https://www.sciencedirect.com/science/article/abs/pii/S000989811100595X#
Ethylene Glycol Toxicity
https://www.ncbi.nlm.nih.gov/books/NBK537009/
Alcohol Dehydrogenases
https://www.sciencedirect.com/topics/chemistry/alcohol-dehydrogenases
Why Is Antifreeze So Delicious?
https://slate.com/news-and-politics/2004/07/why-is-antifreeze-so-delicious.html
Bitter and sweet components of ethanol taste in humans
https://pubmed.ncbi.nlm.nih.gov/10940547/
Alcohol Metabolism: An Update
https://pubs.niaaa.nih.gov/publications/aa72/aa72.htm
Biochemistry, Lactate Dehydrogenase
https://www.ncbi.nlm.nih.gov/books/NBK557536/
Signal transduction and information processing in mammalian taste buds
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723147/
What Are the Toxicological Effects of Ethylene Glycol Poisoning?
https://www.atsdr.cdc.gov/csem/ethylene-propylene-glycol/toxicological_effects.html#:~:text=Ethylene%20glycol%20is%20a%20central,cause%20serious%20or%20fatal%20toxicity
Antifreeze and Engine Coolant Being Bittered Nationwide
https://web.archive.org/web/20121228225407/http://www.cspa.org/news-media-center/news-releases/2012/12/antifreeze-and-engine-coolant-being-bittered-nationwide
The impact of bittering agents on pediatric ingestions of antifreeze
https://pubmed.ncbi.nlm.nih.gov/19571333/
The impact of bittering agents on suicidal ingestions of antifreeze
https://pubmed.ncbi.nlm.nih.gov/18584362/
Toxicology of E-Cigarette Constituents
https://www.ncbi.nlm.nih.gov/books/NBK507184/
Food additive could serve as a safer, more environmentally friendly antifreeze
https://www.eurekalert.org/news-releases/554583
