From Reuters.

1. The U.S. government shut down much of its operations on Wednesday as deep partisan divisions prevented Congress and the White House from reaching a funding deal, setting off what could be a long, grueling standoff that could lead to the loss of thousands of federal jobs.

2. U.S. Defense Secretary Pete Hegseth slammed "fat generals" and diversity initiatives that he said led to decades of decay in the military and told a rare gathering of commanders on Tuesday they should resign if they do not support his agenda.

3. Pfizer and President Donald Trump on Tuesday said they had cut a deal in which the U.S.-based drugmaker agreed to lower prescription drug prices in the Medicaid program to what it charges in other developed countries in exchange for tariff relief.

4. European Union leaders will discuss proposals for a "drone wall" to protect the continent at a summit on Wednesday in Copenhagen, just days after airspace intrusions by unidentified unmanned aircraft forced a temporary closure of Danish airports.

5. Italy said on Tuesday it would stop tracking an international flotilla trying to deliver aid to Gaza with a military vessel, leaving activists vulnerable to Israeli forces.

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